In vivo 1H-MR Spectroscopy of the mouse cervical spinal cord
نویسندگان
چکیده
Introduction In vivo proton magnetic resonance spectroscopy (MRS) is a unique method for non invasive assessment of healthy and pathologic tissue metabolism. Spinal cord (SC) MRS has been reported in human studies [1-4], as well as in rats [5-6], however, no reports have been performed on mice although it should help, in addition to MRI, in the description of the numerous mouse models of SC diseases such as multiple sclerosis and injury. In this work, and as a preliminary step for feasibility and sensitivity studies, we have investigated the possibility of performing single voxel spectroscopy (SVS) on mouse cervical spinal cord.
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